United States of America
- Seymour, a city in New Haven County, Connecticut
- Seymour, city in Jackson County, Indiana
- Seymour, Wayne County Town, Iowa
- Seymour, a city in Webster County, Missouri
- Seymour, census-designated place in Sevier County, Tennessee
- Seymour, the county seat of Baylor County, Texas
- Seymour, a city in the County of Eau Claire, Wisconsin
- Seymour, a city in Lafayette County, Wisconsin
- Seymour, a city in Outagamie County, Wisconsin
South Africa
- Seymour, city of the local municipality of Nkonkobe