Mendoza is a common Spanish surname. The Portuguese version is Mendonça. The name can refer to:
Brazil
- Mendonça, municipality of state of Sao Paulo
Argentina
- Mendoza, a city
- Great Mendonza, the urban agglomeration of the homonymous city
- Mendoza province
- Mendoza River
Peru
- Rodríguez de Mendoza Province, a province of the Amazonas region
- Mendoza, the capital of the province
Venezuela
- Mendoza del Valle del Momboy, a locality in the state of Trujillo