Saint-Louis (in French St. Louis) can have numerous meanings:
Canada
France
- Saint-Louis (Upper Rhine)
- Saint-Louis (Guadeloupe)
- Saint-Louis (Moselle)
- Saint-Louis (Réunion)
- Saint-Louis (Marseille), a neighborhood in the French city of Marseille
- Île Saint-Louis, known island on the Seine a Paris
Haiti
- Saint-Louis-du-Nord, capital of the homonymous arrondissement
- Saint-Louis-du-Sud, arrondissement of Aquin
- Arrondissement of Saint, Louis-du-Nord, arrondissment of the department of the North-West