San Luis, (San Luigi in Spanish), may indicate.
Argentina
- San Luis (province), province ofArgentina
- San Luis, capital of the homonymous province
Brazil
- São Luís Gonzaga do Maranhão, municipality of the state of Maranhão
- São Luiz Gonzaga, municipality of the state of Rio Grande do Sul
Colombia
- San Luis, municipality in the department of Antioquia
- San Luis, municipality in the department of Tolima
- San Luis de Gaceno, municipality in the department of Boyacá
- San Luis de Palenque, municipality in the department of Casanare
- San Luis de Sincé, municipality of the department of Sucre
Costa Rica
- San Luis, district of the canton of Turrubares
Cuba
- San Luis, in the province of Santiago de Cuba
El Salvador
Philippines
- San Luis, municipality of the Agusan del Sur province
- San Luis, municipality of the Aurora province
- San Luis, municipality of the Batangas Province
- San Luis, municipality of the Pampanga province
Guatemala
- San Luis, municipality of the Petén department
- San Luis Jilotepeque, municipality of the department of Jalapa
Honduras
- San Luis, municipality of the department of Comayagua
- San Luis, municipality of the department of Santa Bárbara
Mexico
- San Luis (Chihuahua)
- San Luis (Coahuila)
- San Luis (Michoacán)
- San Luis (Sonora)
- San Luis Potosí (state), a state
- San Luis Potosí, the capital of the homonymous state
Peru
- San Luis, capital of the province of Carlos Fermín Fitzcarrald inAncash
- District of San Luis, in the province of File
- District of San Luis, in the province of Cañete