San Carlos (Spanish language, corresponding to Italian San Carlo) can refer to different toponyms:
Argentina
- San Carlos, Argentine department of the province of Salta
- San Carlos, capital of the aforementioned department
- San Carlos, city of the province of Corrientes, in the department of Ituzaingó
Bolivia
- San Carlos, municipality of department of Santa Cruz
Chile
Colombia
- San Carlos, common in department of Antioquia
- San Carlos, common in department of Córdoba
- San Carlos de Guaroa, common in Meta department
Costa Rica
- San Carlos, district of the canton of Tarrazú
- Canton of San Carlos, canton of the province of Alajuela
Ecuador
- San Carlos, a town in the province of Los Ríos
El Salvador
Philippines
- San Carlos, city in the Negros Occidental province
- San Carlos, city in the Pangasinan province
Guatemala
- San Carlos Alzatate, municipality of the department of Jalapa
- San Carlos Sija, municipality of the Quetzaltenango department
- Nuevo San Carlos, municipality of the department of Retalhuleu
Nicaragua
- San Carlos, capital of the department of Río San Juan
United States of America
- San Carlos, census-designated place of Gila County, Arizona
- San Carlos, Inyo County Settlement, California
- San Carlos, city of San Mateo County, California
- San Carlos, census-designated place in Hidalgo County, Texas
Uruguay
- San Carlos, city of the department of Maldonado
Venezuela
- San Carlos, state capital of Cojedes
- San Carlos, city in the state ofAmazonas