Columbus, first name English of Christopher Columbus which occurs in numerous toponyms
United States of America
- Columbus, capital ofOhio
- Columbus, the county seat of Polk County, North Carolina
- Columbus, a city in Burke County, North Dakota
- Columbus, the county seat of Muscogee County, Georgia
- Columbus, Adams County village, Illinois
- Columbus, county seat of Bartholomew County, Indiana
- Columbus, the county seat of Cherokee County, Kansas
- Columbus, a city in Hickman County, Kentucky
- Columbus, Light County township, Michigan
- Columbus, a township in St. Clair County, Michigan
- Columbus, city of Anoka County, Minnesota
- Columbus, the county seat of Lowndes County, Mississippi
- Columbus, City of Missouri
- Columbus, the county seat of Stillwater County, Montana
- Columbus, capital of Platte County, Nebraska
- Columbus, a city in Chenango County, New York
- Columbus, village of Luna County, New Mexico
- Columbus, Warren County Township, Pennsylvania
- Columbus, the county seat of Colorado County, Texas
- Columbus, a city in Columbia County and Dodge County, Wisconsin