The term Rio Grande (in Portuguese and in SpanishRío Grande) is a toponym that literally means "great river" and can refer to numerous rivers and localities, or even to other meanings:
Argentina
- Río Grande (Jujuy), city in the Jujuy province
- Río Grande (Tierra del Fuego), city in the province of Tierra del Fuego
- Río Grande, district of the department of Malargüe, in province of Mendoza
Bolivia
- Río Grande (Potosí), city in department of Potosí
- Río Grande (Tarija), city in department of Tarija
Brazil
- Rio Grande (Bahia), city in the state of Bahia
- Rio Grande (Espírito Santo), city in the state ofEspírito Santo
- Rio Grande (Pernambuco), city in the state of Pernambuco
- Rio Grande (Rio de Janeiro), city in the state of Rio de Janeiro
- Rio Grande (Rio Grande do Sul), city in the state of Rio Grande do Sul
- Rio Grande da Serra, city in the state of St. Paul
- Rio Grande do Norte, been in the eastern end of the country
- Rio Grande do Piauí, city in the state of Piaui
- Rio Grande do Sul, southern state of the country
- Rio Grande dos Lopes, city in the state of Maranhão
Chile
- Río Grande (Antofagasta), city in the Antofagasta region
Costa Rica
- Río Grande (Alajuela), city in the province of Alajuela
- Río Grande (Guanacaste), city in the Guanacaste province
- Río Grande (Puntarenas), city in the province of Puntarenas
- Río Grande (San José), city in the province of San José
Cuba
- Río Grande (Holguín), city in the province of Holguín
- Río Grande (Las Tunas), city in the province of Las Tunas
- Río Grande (Sancti Spíritus), city in the Province of Sancti Spíritus
Puerto Rico
- Río Grande (Puerto Rico), City of Puerto Rico
Other
- Rio Grande, a tributary of the Mamoré river in Bolivia
- Rio Grande, a river of the Brazil tributary of the São Francisco River
- Rio Grande, a tributary of the Paraná River, Brazil
- Río Grande, river of the Nicaragua
- Río Grande, river of the Peru
- Rio Grande, river American of the southern states that flows into the Gulf of Mexico It is called Río Bravo or, formally, the Río Bravo del Norte in Mexico
- Rio Grande, river Venezuelan also known as Río Caucagua